Search on: ANGIOTENSIN-CONVERTING ENZYME INHIBITORS 
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Descriptor English:   Angiotensin-Converting Enzyme Inhibitors 
Descriptor Spanish:   Inhibidores de la Enzima Convertidora de Angiotensina 
Descriptor Portuguese:   Inibidores da Enzima Conversora da Angiotensina 
Synonyms English:   Kininase II Inhibitors
ACE Inhibitors  
Tree Number:   D27.505.519.389.745.085
Definition English:   A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. 
Indexing Annotation English:   protease inhib & antihypertensives; DF: ACE INHIB
History Note English:   88; ANGIOTENSIN I-CONVERTING ENZYME INHIBITOR was see TEPROTIDE 1991-93 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   22832 
Unique Identifier:   D000806 

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